| Randomization Arm |
Sensitivity (%)* |
Specificity (%)* |
|
| Female patients |
| Morphine (n = 102) |
65.9 |
60.7 |
| Placebo (n = 92) |
84.0 |
52.2 |
| Difference |
-18.1
(-30.0, -6.2) |
8.5 (-5.4, 22.4) |
| Male patients |
| Morphine (n = 73) |
76.2 |
74.2 |
| Placebo (n = 73) |
78.7 |
57.7 |
| Difference |
2.5 (-16.1, 11.1) |
16.5
(1.4, 31.6) |
| All patients |
| Morphine (n = 175) |
71.1 |
65.2 |
| Placebo (n = 165) |
80.6 |
53.8 |
| Difference |
-9.5
(-18.5, -0.5) |
11.4
(1.0, 21.8) |
|
| * Standard of reference was the histologic diagnosis of appendicitis in patients who underwent surgery and no rehospitalization for those who did not undergo surgery. Numbers in parentheses are 95% CIs. See Figure for numerators and denominators of sensitivity and specificity. |
| P < .05 for difference between the morphine arm and placebo arm. |
|