Figure 3b. Screening mammograms in an 85-year-old woman with large fatty breasts show bilateral calcified vessels. These technically suboptimal screening mammograms were interpreted as negative. Cancer was detected in the right upper outer quadrant on the next scheduled screening mammogram 12 months later. (a) CC and (b) MLO views show deficiencies in mammographic technique on all but the right CC view. The anterior aspect of the breast was not included on the right breast MLO view or the left breast CC view. No pectoral muscle is included in the image field on the left MLO view. A prominent skin fold in the left CC view indicates poor breast compression. None of these technical factors were judged to have affected the detection of the extensive pleomorphic calcifications in the upper outer portion of the right breast (arrows). (c) Regional pleomorphic calcifications occupy a 5-cm area on this photographic enlargement of the right MLO view. (d) CAD marked the large area of calcifications in both CC and MLO views in several locations in the right upper outer quadrant. Each of the four views also has one false-positive mark over arterial calcifications. Specifically, the most lateral mark on the right CC view and the most inferior mark on the MLO view are false-positive.