Figure 3. Coronal dynamic contrast-enhanced T1-weighted spin-echo MR images (100/10) of the ischemic leg and the normal leg 3 months after ischemia induction. The first image was obtained before contrast material injection; the last image, after contrast material injection. The other images were obtained pixel by pixel with the formula: 
SI = SI(t) - SIpre. Signal intensity enhancement started to become relevant approximately 30 seconds after injection and reached a plateau after 60 seconds. Arrows = affected area.