Figure 8. Graph shows receiver operating characteristic comparison of the various methods of cancer detection. No single test or combination of tests showed sufficient sensitivity for prostate cancer detection. Routine sextant biopsy, at which all patients were presumed to have tumor prior to biopsy, is represented at the top right corner, with a presumed sensitivity of 1 and a specificity of 0. Bx = biopsy, CDI = color Doppler US, GS = gray-scale US.