Figure 10a. MR imaging of mesial temporal sclerosis by using temporal dual phased-array coils. (a) Coronal T1-weighted SPGR volume acquisition (23/4; flip angle, 45°) demonstrates volume loss and architectural distortion of the left hippocampus, consistent with mesial temporal sclerosis. Spatial resolution is 0.6 mm3/voxel. Arrow = alveus of left hippocampus. (b) Coronal T2-weighted fast SE image (4,875/108) in the same patient demonstrates a subtle increase in signal intensity (arrow) and an absence of internal architecture in the diseased left hippocampus. Compare with the well-defined internal architecture of the normal right hippocampus, where the low-signal-intensity perforant pathway (arrowhead) is visible. Spatial resolution is 0.4 mm3/voxel.