Figure 4c. Images of occult T3 carcinoma in a 61-year-old woman. (a) Specimen radiograph depicts a cluster of microcalcifications (arrow) that had been the indication for an excision biopsy. No other focus suspicious for cancer was seen. (b) Histologic slide of the marked area (box) in a shows breast parenchyma with little fibrosis at low magnification. (Hematoxylin-eosin stain; original magnification, x25.) (c) Histologic specimen at high magnification of the marked region (box) in b reveals small clusters of malignant epithelial cells (arrows) in the fibrous tissue. Similarly dispersed tumor cell clusters were found throughout the entire breast. (Hematoxylin-eosin stain; original magnification, x250.)