Figure 10b. T1-weighted MR images with color voxel compression mapping overlay in a 46-year-old man with familial AD. Images were obtained in (a) transverse, (b) coronal, and (c) sagittal planes over 30 months during which symptoms developed. Green and blue areas demonstrate interval volume loss, particularly in temporal lobes and in other neocortical areas. (Images courtesy of Nick C. Fox, MD, MRCP, National Hospital for Neurology and Neurosurgery, London, England.)