Figure 8a. Coronal T2-weighted fast spin-echo MR images (repetition time msec/echo time msec, 2,700/80) in (a, b) a patient with AD and (c, d) an age-matched control subject. (a, b) The patient with AD has severe bilateral hippocampal atrophy (arrows). Compare this with (c, d) normal hippocampus (arrows) in the control subject. Note that b is a close-up of a, and d is a close-up of c. (Images courtesy of Daniel P. Barboriak, MD, Duke University Medical Center, Durham, NC.)