Figure 3b. Retinoblastoma in 3
-year-old boy. (a) Transverse gadolinium-enhanced T1-weighted fat-suppressed MR image (575/15) of right eye shows tumor mass (arrowheads) surrounded by hyperintense subacute subretinal bleeding. Notice local thickening of choroid (black arrow) lateral to the optic nerve caused by massive tumor invasion. Increased SI (white arrow) posterior to the eyeball is present and was suspicious for postlaminar tumor invasion. (b) Transverse T2-weighted MR image (2200/120) shows characteristic hypointense retinoblastoma surrounded by hyperintense subretinal fluid. (c) Histopathologic specimen shows massive invasion of retinoblastoma (R) into the choroid (C). Sclera (S) is not affected. (Hematoxylin-eosin; original magnification, x10 objective.) (d) Histopathologic specimen shows same findings as in c and postlaminar optic nerve (O) invasion (arrow). (Hematoxylin-eosin; original magnification, x20 objective.)