Figure 3. Gross tumor progression in rats treated with combined RF ablation and radiation therapy. A, Tumor (arrow) with 11-mm diameter at day 0, prior to therapy. B, At day 4, after RF ablation and 20-Gy radiation therapy, beginning of involution is evident in tumor (arrow). C, At day 7, granulation tissue (arrow) can be seen, and there are signs of hair regrowth. (All that will remain by day 25 is scar tissue.) D, Scar (arrow) on chest wall at day 120.