Figure 1b. Transverse postcontrast dynamic subtracted MR images (270/4.6 [repetition time msec/echo time msec] and 90° flip angle) obtained at standard two-dimensional (2D) gradient-echo dynamic MR imaging (temporal resolution, 69 seconds per dynamic acquisition; imaging matrix, 256 x 256) of 53-year-old woman with invasive ductal cancer. Same section is displayed throughout dynamic series at (a) 69 seconds, (b) 2 minutes 18 seconds, (c) 3 minutes 27 seconds, and (d) 4 minutes 36 seconds after contrast material injection. Note that contrast between cancer (arrow) and normal fibroglandular tissue on both sides (arrowheads) is best in early postcontrast phase (a). Owing to strong washout effect in the cancer and progressive increase in signal intensity of normal parenchyma, cancer can be overlooked already on third postcontrast image (c). Assessment of fine morphologic details will not be feasible in these delayed postcontrast images because of lack of contrast between cancer and normal tissue.