Figure 1e. Selected serial frontal chest radiographs in 44-year-old man with laboratory-confirmed SARS at each of five milestones. (a) On radiograph acquired at admission (first milestone, 3 days after symptom onset), there was an area of opacification in the right lower zone. (b) On radiograph acquired at the start of ribavirin (second milestone, 5 days after symptom onset), a new area of opacification is seen to have developed in the left lower zone. (c) On radiograph acquired at first pulse of corticosteroid (third milestone, 8 days after symptom onset), new involvement of the right upper zone is seen. The other areas of opacification have enlarged and become less well defined. (d) Worst radiograph (fourth milestone, 11 days after symptom onset) shows widespread lung opacification affecting middle and lower zones bilaterally that is worse on the right. (e) Radiograph obtained before hospital discharge (fifth milestone, 24 days after symptom onset) shows that opacification has largely resolved. Reticulations were present in both the middle and lower zones.