Figure 7: Chemical shift MR/MR spectroscopic imaging (1000/18; bandwidth, 1000 Hz; 512 points with two signals acquired). Transverse short-echo-time chemical shift image (left) acquired at 0.5 T in a presymptomatic patient with Huntington disease shows strong elevation of glutamate (right: upper spectrum) in the head of the putamen. Unaffected thalamus (right: lower spectrum) is shown for comparison. (Image courtesy of Robert Prost, PhD, Medical College of Wisconsin, Milwaukee, Wis.)