Figure 2: Polyp CAD manager window used with SURF. The left panel lists polyp candidates presented to each reader. During reference standard setting, all panels were used to characterize TP and FP polyp candidates, assign a confidence level, and rate each feature according to parameters shown. During blinded reader review, only the subpanel (indicated by the dashed box) was used to enter confidence levels for 2D or combined 2D and 3D viewing (ie, study readers were blinded to information concerning additional features and optical colonoscopy results).