Figure 2: 1H MR spectrum analyzed with LCModel (version 6.1-4) output of point-resolved spatially localized spectroscopy in a healthy adult subject. Spectra were recorded at 1.5 T (Intera; Philips Medical Systems, Best, the Netherlands) from the occipital lobe (repetition time msec/echo time msec, 2000/23; 128 signals acquired; voxel size, 8 cm3). In vivo spectrum (thin upper spectrum) was estimated with LCModel output (thick upper spectrum); the difference between spectra is plotted at the bottom. Above the difference spectrum is the baseline spline estimate, determined with LCModel. Inserted table at right displays estimated metabolite concentrations and Cramer-Rao minimum variance bounds. Cho = choline, Conc. = concentration, Cr = creatine, FWHM = full width at half maximum, Ins = myo-inositol, SD = standard deviation, tCr = total creatine.