Figure 3e: GBM in 56-year-old woman. Transverse (a) preoperative T2-weighted MR image (3600/96), (b) contrast-enhanced T1-weighted MR image (440/14), and (c) ADC map show irregularly shaped enhancing tumor (arrows in a) with perifocal edema in left mediofrontal lobe. Minimum ADC value was 0.72 x 10–3 mm2 · sec–1. (d) Postoperative contrast-enhanced transverse T1-weighted MR image (440/14) shows gross total removal of the tumor. (e) Contrast-enhanced transverse T1-weighted MR image (440/14) 9 months after surgery shows a patchy enhancing lesion (arrow). The lesion enlarged later, and gamma knife therapy was performed. With further progression of the disease, the patient died 1.5 years after initial treatment.