Figure 5: Transverse MR images of right frontal region glioblastoma multiforme in 69-year-old man. Lesion was correctly classified as high-grade primary tumor because of enhancement, restricted diffusion, necrosis, and elevated perfusion. A, Fluid-attenuated inversion-recovery (10 000/120; inversion time, 2200 msec; field of view, 220 mm; matrix, 256 x 256; section thickness, 5 mm; intersection gap, 0 mm; number of signals acquired, two) and, B, contrast-enhanced T1-weighted spin-echo (600/11; field of view, 220 mm; matrix, 256 x 256; section thickness, 5 mm; intersection gap, 0 mm; number of signals acquired, one) transverse images demonstrate enhancement (*) with hyperintense surrounding edema (arrowheads) and necrotic component (arrow). C, Diffusion-weighted image and, D, ADC map (10 000/118; b values, 0 and 1000 sec/mm2) show restricted diffusion where the lowest ADC obtained was 0.88 x 10–3 mm2/sec. E, Perfusion image (2000/75; field of view, 240 mm; section thickness, 5 mm; number of signals acquired, one) shows regions of elevated rCBV with measured ratios above 2.97.