Figure 2a: Graphs show quantitative data used to analyze the effects of antiangiogenic treatment. Note that VTA treatment resulted in a significant reduction (*) of (a) the 
R2* (control group, 20 tumors; VTA group, 20 tumors) and (b) the VVF (control group, 20 tumors; VTA group, 20 tumors) values. (c) Moreover, results of a perfusion assay with fluorescent microbeads corroborated the MR results and showed a 72% reduction in tumor perfusion after VTA treatment (control group, three tumors; VTA group, four tumors). In a–c, data are mean values and error bars indicate standard error of the mean. (d) Morphometric analysis revealed an inverse correlation of the grade of tumor thrombosis and/or necrosis with the R2* (
, r = –0.83) and the VVF (
, r = –0.74) values.