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Radiology, Vol 118, 645-651, Copyright © 1976 by Radiological Society of North America

ARTICLES

Pulmonary distribution of an inhaled radioaerosol in obstructive pulmonary disease

MS Lin and DA Goodwin

Pulmonary distribution of an inhaled radioaerosol was analyzed in 20 cases of chronic obstructive pulmonary disease (COPD) and 8 of other OPD. Nonciliary/ciliary partition of the distribution correlated with the severity of airway obstruction and approximated 3:1 in mild and 1:3 in very severe obstruction. In nuclear images, the distribution featured contrast abnormalities of hyperdeposition and hypodeposition. Intense hyperdeposition most commonly occurred in hilar and perihilar large airways. In isolated instances, hyperdeposition almost certainly occurred focally at sites of partial bronchial obstruction and diffusely by expiratory trapping; hypodeposition occurred distally to bronchial obstruction and in areas of parenchymal loss.


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[Abstract] [Full Text]


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