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Radiology, Vol 119, 731-731, Copyright © 1976 by Radiological Society of North America

ARTICLES

Preparation and evaluation of 111In-labeled leukocytes as an abscess imaging agent in dogs

ML Thakur, RE Coleman, CG Mayhall and MJ Welch Jr

Leukocytes labeled with 111In chelated with 8-hydroxyquinoline were evaluated as an abscess imaging agent in dogs. The labeling technique is simple and offers 75-95% efficiency. The half-clearance time of the labeled leukocytes is 6-10 hours, and the target-to-blood activity ratios are higher than those of other compounds now in use. The authors suggest that 111In-labeled leukocytes replace 67Ga citrate as a routine abscess imaging agent.




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