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Radiology, Vol 120, 349-350, Copyright © 1976 by Radiological Society of North America

ARTICLES

Computed tomography in adrenoleukodystrophy. Correlation of radiological and histological findings

EE Duda and PR Huttenlocher

Computed tomograms (CT) demonstrated symmetrical low-density lesions in the white matter of the posterior portion of the cerebral hemispheres in a 9-year-old boy with adrenoleukodystrophy (Schilder's disease). Biopsy of the brain in an area that appeared normal on the CT scan showed profound loss of myelinated fibers and oligodendroglia; the white matter had been replaced by a rather loose acellular stroma consisting of astroglial cells and blood vessels.




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Copyright © 1976 by the Radiological Society of North America.