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Radiology, Vol 120, 623-626, Copyright © 1976 by Radiological Society of North America

ARTICLES

Imaging of tumors involving bone with 13N-glutamic acid

JM McDonald, AS Gelbard, LP Clarke, TR Christie and JS Laughlin

Nitrogen-13 labeled L-glutamic acid was evaluated as an imaging agent for tumors involving bone. The enzymatically prepared labeled compound was administered intravenously to dogs with spontaneous tumors, and tumor uptake was determined with a gamma camera and rectilinear scanner. These tumors were well visualized with 13N-glutamic acid, and the results compared favorably with uptake studies performed on the same animals with 99mTc-diphosphonate.




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Copyright © 1976 by the Radiological Society of North America.