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Radiology, Vol 122, 137-141, Copyright © 1977 by Radiological Society of North America

ARTICLES

Diagnosis of progressive multifocal leukoencephalopathy by computed tomography

BA Carroll, B Lane, D Norman and D Enzmann

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system which predominantly affects immunologically compromised hosts. The distinctive CT appearance in three documented cases includes low-density lesions of central and convolutional white matter with scalloped lateral borders. Lesions demonstrate no mass effect or contrast material enhancement. Findings are discussed with reference to other entities which may produce a similar CT appearance.


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