Radiology, Vol 122, 183-186, Copyright © 1977 by Radiological Society of North America
Noninvasive determination of glomerular filtration rate using x-ray fluorescence
N Alazraki, JW Verba, JE Henry, R Becker, A Taylor Jr and SE Halpern
Accurate glomerular filtration rates (GFR) can be calculated based on the
infusion of small amounts of nonradioactive iothalamate and collection of
plasma samples for assay by x-ray fluorescence. This innovation permits
frequent clearance determinations in patients without the hazard of
repeated radiation exposure and without the necessity of catheterization of
the bladder for urine samples. Thus, the technique becomes feasible in
children, transplant patients, and other needing accurate and frequent GFR
determinations.
