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Radiology, Vol 124, 419-424, Copyright © 1977 by Radiological Society of North America

ARTICLES

Myocardial imaging with 123I-hexadecenoic acid

ND Poe, GD Robinson Jr, FW Zielinski, WR Cabeen Jr, JW Smith and AS Gomes

123I-hexadecenoic acid is a terminally iodinated, 17-carbon fatty acid analog which is rapidly degraded in the myocardium. By determining regional myocardial distribution patterns and clearance rates, it may become useful as a single agent for estimating regional myocardial perfusion and for distinguished viable ischemic tissue from infarcted tissue. The high count rates obtainable with the iodine label permit acquisition of qualitative multiprojection images in only 3 min. per view, or quantifiable single projection high count images in 10 min. Ischemic defects may be observed in anginal patients without subjecting them to stress.




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Copyright © 1977 by the Radiological Society of North America.