Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hessel, S. J.
Right arrow Articles by Abrams, H. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hessel, S. J.
Right arrow Articles by Abrams, H. L.

Radiology, Vol 127, 413-418, Copyright © 1978 by Radiological Society of North America

ARTICLES

Detection of myocardial ischemia in vitro by computed tomography

SJ Hessel, DF Adams, PF Judy, MC Fishbein and HL Abrams

The applicability of CT in the delineation of ischemic myocardium is defined. Twenty-six dogs had their left anterior descending coronary artery occluded, and radiolabeled microspheres were injected into the left atrium to measure myocardial blood flow. From 30 minutes to 7 weeks after coronary occlusion the hearts were excised and scanned in a CT head scanner. An unbiased observer divided selected CT scans slices into normal, abnormal, and borderline areas of attenuation coefficients; these were correlated with blood flow measurements and a progressive decrease in flow from normal to borderline and borderline to abnormal segments was found. As early as 2 hours after coronary arterial occlusion, areas of reduced attenuation coefficient, corresponding to regions of reduced blood flow, were seen. Areas of increased attenuation were seen in regions containing microcalcifications and fibrosis in several longer term experiments. Areas of reduced blood flow were visible immediately after coronary arterial occlusion with intravenous iodinated contrast material (1 ml/kg). CT detection of regions of reduced blood flow defined by radiolabeled microsphere is a promising means of detecting and sizing myocardial infarcts.


This article has been cited by other articles:


Home page
 RadiologyHome page
U. J. Schoepf, C. R. Becker, B. M. Ohnesorge, and E. K. Yucel
CT of Coronary Artery Disease
Radiology, July 1, 2004; 232(1): 18 - 37.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1978 by the Radiological Society of North America.