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Radiology, Vol 128, 359-365, Copyright © 1978 by Radiological Society of North America

ARTICLES

Benefit/risk analysis of aggressive mammographic screening

SH Fox, M Moskowitz, EL Saenger, JG Kerelakes, J Milbrath and MW Goodman

Based on the results of aggressive screening of 20,000 women and an annual average midbreast absorbed dose of 1 rad per year, the authors describe a model for estimating the benefit/risk ratio for mammography in screening populations of asymptomatic, randomly selected women. Benefits in terms of breast-cancer deaths averted over not screening are estimated. The "worst-case" estimate of the benefit/risk ratio for five annual mammographic examinations on randomly selected asymptomatic women age 35-49 at the start of screening is 3.4 +/- 1.1 to 1. The corresponding "most probable" estimate is 8.0 +/- 3.1 to 1.


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J R Beckett, C J Kotre, and J S Michaelson
Analysis of benefit:risk ratio and mortality reduction for the UK Breast Screening Programme
Br. J. Radiol., May 1, 2003; 76(905): 309 - 320.
[Abstract] [Full Text] [PDF]


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