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Radiology, Vol 130, 159-164, Copyright © 1979 by Radiological Society of North America

ARTICLES

Computed tomography in oculocraniosomatic disease (Kearns-Sayre syndrome)

RS Seigel, JF Seeger, TO Gabrielsen and RJ Allen

Computed tomography (CT) in patients with oculocraniosomatic disease (OCSD) or Kearns-Sayre syndrome has not been previously reported to the authors' knowledge. CT scans were performed in 6 children and 3 adults with OCSD. Abnormalities in children included: intracranial calcifications (4 patients); white matter disease (3 patients); cerebellar hypoplasia (1 patient); and scattered areas of decreased density in the cerebellar hemispheres, mesencephalon, and thalamus (1 patient). CT scans were normal in all adults. OCSD should be considered in the differential diagnosis in patients with intracranial calcification and white matter disease.




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