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Radiology, Vol 130, 241-244, Copyright © 1979 by Radiological Society of North America


ARTICLES

Pharmacologic enhancement of gallium-67 tumor-to-blood ratios for EMT-6 sarcoma (BALB/c mice)

SM Larson, JS Rasey, Z Grunbaum and DR Allen

At various intervals after intravenous injection of carrier-free 67Ga- citrate, iron dextrane or deferoxamine mesylate was injected into EMT-6 tumor-bearing BALB/c mice. After treatment, rapid clearance of 67Ga from soft tissues was observed. Tumor uptake was not greatly affected, and so increased tumor-to-blood ratios were observed. The authors conclude that these drugs can enhance target-to-nontarget uptake ratios for tumors.





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Copyright © 1979 by the Radiological Society of North America.