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Radiology, Vol 130, 473-475, Copyright © 1979 by Radiological Society of North America

ARTICLES

Assessment of renal function following irradiation of the intact spleen for Hodgkin disease

BM Birkhead, CE Dobbs, MF Beard, JW Tyson and EA Fuller

Twenty-three patients with clinical Stage IA-IIIB Hodgkin disease underwent extended-field radiotherapy, including the intact spleen. In 17 of those patients, there was little evidence of renal dysfunction resulting from partial irradiation of the left kidney, which is inherent in such treatment. While isotopic images revealed an anatomic defect in the upper pole of the left kidney in one-third of the patients, dynamic studies showed that this anatomic alteration was not accompanied by any demonstrable dysfunction. Consistently normal serum BUN and creatinine levels in all patients tended to affirm that conclusion.




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