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Radiology, Vol 131, 23-26, Copyright © 1979 by Radiological Society of North America

ARTICLES

Ceruletide-assisted cholecystography: a clinical assessment

SM Wetzner, ME Vincent and AH Robbins

The cholecystokinetic effect of ceruletide, a synthetic decapeptide similar in action to cholecystokinin, was examined in both a randomized and nonrandomized study in 81 patients scheduled for routine oral cholecystograms. Intramuscular injection of ceruletide in a dose of 0.3 microgram/kg resulted in a mean maximum contraction of the gallbladder of 68% and a mean time until maximum contraction of 28 minutes. Visualization of the cystic duct occurred in 57 patients (70%); the common duct was seen in 67 (83%). Ceruletide demonstrated superior gallbladder contraction when compared to fatty meals and demonstrated no interference with a subsequent upper gastrointestinal series.


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G. E. Vist, K. B. Hagen, P J Devereaux, D. Bryant, D. T. Kristoffersen, and A. D. Oxman
Systematic review to determine whether participation in a trial influences outcome
BMJ, May 21, 2005; 330(7501): 1175.
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