Radiology, Vol 133, 511-513, Copyright © 1979 by Radiological Society of North America
Polyvinylpyrrolidone contrast enhancement: abscess imaging
SW Young and D Enzmann
Rabbits with thigh abscesses received an intravenous solution of
polyvinylpyrrolidone (PVP) and metallic salts, resulting in a dense ring of
contrast enhancement as determined by computed tomography (CT). Enhancement
increased during the first two weeks, stabilized, then decreased to control
levels at eight weeks. After antibiotics the ring of enhancement appeared
to mark the abscess perimeter as it regressed. Normal muscle density did
not change. The magnitude and duration of enhancement would improve CT
detection of small lesions and be useful in evaluating the efficacy of
therapy.
