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Radiology, Vol 133, 597-599, Copyright © 1979 by Radiological Society of North America

ARTICLES

Iodine absorption from the gastrointestinal tract during hypaque-enema examination

RL Eisenberg, MW Hedgcock, JD Shanser, RJ Brenner, RK Gedgaudas and WM Marks

Iodinated contrast agents administered intravenously or intra- arterially may cause serious reactions in hypersensitive patients. Oral administration of Hypaque (diatrizoate sodium) results in minimal absorption of iodine, but the amount of iodine absorbed with Hypaque- enema studies is unreported. Hypaque-enema examinations were performed in 20 normal, nonsensitive patients and increased serum iodine levels ten to 200 times base-line values, peaking after approximately one hour in patients who had measurements obtained for four hours. Therefore, before Hypague-enema studies, patients must be carefully questioned about their tolerance of iodinated contrast agents, and preparations should be made for possible serious hypersensitivity reactions.


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B. M. Plavsic, A. C. Newman, W. L. Reuther, J. A. Terry, and V. H. Drnovsek
Peripheral Blood Eosinophilia Associated with Gastrointestinal Administration of Iodinated Contrast Media
Am. J. Roentgenol., March 1, 2003; 180(3): 751 - 753.
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