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Radiology, Vol 139, 465-469, Copyright © 1981 by Radiological Society of North America

ARTICLES

Radionuclide localization of lower gastrointestinal hemorrhage

GG Winzelberg, JW Froelich, KA McKusick, AC Waltman, AJ Greenfield, CA Athanasoulis and HW Strauss

The authors prospectively evaluated the usefulness of abdominal radionuclide scintigraphy using 99mTc-labeled red cells as a means of monitoring for intermittent gastrointestinal bleeding over a 24-hour period in both control and actively bleeding populations. Of 32 patients with documented hemorrhage, 29 had positive scintiscans (sensitivity, 91%; 9% false negatives). Of 18 nonbleeding patients, 17 had negative scintiscans (specificity, 95%; 5% false positives). 12 of 29 patients bled from 6 to 24 hours after the study was begun. Scintiscans were positive in patients with transfusion requirements of greater than or equal to 500 ml/24 hr. The authors conclude that abdominal scintigraphy with 99mTc-labeled red cells is an effective method of detecting gastrointestinal bleeding.




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