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Radiology, Vol 140, 11-15, Copyright © 1981 by Radiological Society of North America

ARTICLES

Prekallikrein-Kallikrein conversion rate as a predictor of contrast material catastrophies

EC Lasser, JH Lang, SG Lyon, AE Hamblin and MM Howard

An in vitro is described that attempts to detect patients with a potential for adverse systemic reactions to contrast material. This test involves measuring the rate of conversion of prekallikrein to kallikrein under certain standard conditions. In a preliminary retrospective study, the test could be used to identify such patients with a sensitivity of 88%, a specificity of 82%, and a predictive value of 79%.




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