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Radiology, Vol 141, 185-190, Copyright © 1981 by Radiological Society of North America

ARTICLES

97Ru-DMSA for delayed renal imaging

ZH Oster, P Som, MC Gil, AG Goldman, RG Fairchild, GE Meinken, SC Srivastava, HL Atkins, P Richards and AB Brill

Dimercaptosuccinic acid (DMSA) was labeled with 97Ru both with and without the addition of SnCl.2H2O. The tin-containing preparation was found to induce higher cortical deposition of 97Ru-DMSA than the tin- free preparation. Visualization of the renal cortex was excellent 4 to 48 hours after injection in normal dogs with renal insufficiency. It is concluded that 97Ru-(Sn+2)-DMSA is a potentially useful renal imaging agent when delayed scintigraphy is necessary because of decompensaton of the kidneys.




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