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Radiology, Vol 143, 355-360, Copyright © 1982 by Radiological Society of North America

ARTICLES

Radiographic changes in primary osteogenic sarcoma following intensive chemotherapy. Radiological-pathological correlation in 63 patients

J Smith, RT Heelan, AG Huvos, B Caparros, G Rosen, C Urmacher and JF Caravelli

Sixty-three patients with osteogenic sarcoma of the long bones, all of whom were treated with chemotherapy, demonstrated striking and unusual radiographic changes. Patients with a "good" radiographic response (48%) showed the most dramatic changes, including medullary sclerosis, prominent periosteal new bone formation, and disappearance of the soft- tissue mass; and these findings correlated well with the histological grading of the surgical specimens. Radiographic evaluation of patients receiving chemotherapy for osteogenic sarcoma is a valuable method of assessing response.




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Copyright © 1982 by the Radiological Society of North America.