Radiology, Vol 144, 509-512, Copyright © 1982 by Radiological Society of North America
Subjective responses and albuminuria induced by ioxaglate during renal angiography in man
PE Nilsson, SL Holtas and LT Tejler
The degree of albuminuria induced by renal arteriography with the monoacid
dimeric contrast medium ioxaglate was studied in 19 patients. Ioxaglate did
not cause significant changes in urinary albumin concentrations (median
concentration after angiography = 0.022 g/g creatinine). The results with
ioxaglate are compared with those of an identically designed study
performed earlier with the contrast media metrizoate and metrizamide, in
which both caused significantly increased concentrations of urinary albumin
(1.1 g/g creatinine and 0.96 g/g creatinine, respectively). The degree of
pain/heat sensation following semiselective renal arteriography with
metrizoate and ioxaglate was also compared using a visual analog scale in
34 patients. Ioxaglate caused no pain and a significantly lower heat
sensation than metrizoate.
