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Radiology, Vol 146, 687-689, Copyright © 1983 by Radiological Society of North America


ARTICLES

The use of glucagon in hydrostatic reduction of intussusception: a double-blind study of 30 patients

EA Franken Jr, WL Smith, SM Chernish, JB Campbell, BD Fletcher and HS Goldman

Thirty patients were referred for hydrostatic reduction of ileocolic intussusception. Children with suspected gangrenous bowel or sensitivity to glucagon were excluded from the investigation. A standard protocol for the procedure was used in all patients, including the intravenous administration of glucagon or placebo (0.05 mg/kg) when the intussusception was encountered. Successful reduction was achieved in 53% of both control and glucagon-treated patients. Analysis of the length of the procedure and the ease of reduction of the intussusception indicated no difference in the two groups. This multicenter double-blind study failed to show any therapeutic value of glucagon in hydrostatic reduction of intussusception.





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