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Radiology, Vol 147, 517-519, Copyright © 1983 by Radiological Society of North America

ARTICLES

Ultrasound in the diagnosis of hepatocellular carcinoma associated with cirrhosis

M Cottone, MP Marceno, A Maringhini, F Rinaldi, G Russo, E Sciarrino, M Turri and L Pagliaro

A total of 100 cirrhotic patients with clinically suspected neoplastic transformation was assessed prospectively with ultrasound. Ultrasound was diagnostic in 27/30 patients who had a final diagnosis of hepatocellular carcinoma (sensitivity 90%); there were five false- positive examinations (specificity 93%). The positive predictive value of the test was 84.4%; negative predictive value was 95%. Three different ultrasound patterns were observed in hepatocellular carcinoma: increased reflectivity, decreased reflectivity, and mixed echo pattern. Ultrasound can be used as a safe, effective first-line screening test for cirrhotic patients with clinically suspected neoplastic transformation.


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