Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Becker, G. J.
Right arrow Articles by Klatte, E. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Becker, G. J.
Right arrow Articles by Klatte, E. C.

Radiology, Vol 148, 663-670, Copyright © 1983 by Radiological Society of North America

ARTICLES

Low-dose fibrinolytic therapy. Results and new concepts

GJ Becker, FE Rabe, BD Richmond, RW Holden, HY Yune, RS Dilley, NU Bang, JL Glover and EC Klatte

The authors report their experience with the first 57 infusions (50 patients) in an ongoing study of local low-dose fibrinolysis for treatment of thromboembolic disease. Complete lysis occurred in nearly half of cases, while some therapeutic effect was demonstrable in more than two thirds. Success seems to be most directly related to the type of vessel infused, with the greatest success seen in vessels with no alternate pathways for egress of the fibrinolytic agent. Chronic fibrin deposits could also be treated with this technique. Since new thrombus formation occurs in a significant percentage of patients during local fibrinolytic therapy, the authors recommend cautious use of concomitant continuous intravenous heparin at a dosage sufficient to maintain the partial thromboplastin time at 1.5 times normal. While fibrinolytic therapy is usually not curative, it frequently facilitates detection of the underlying lesion, permitting definitive therapy.


This article has been cited by other articles:


Home page
 ANGIOLOGYHome page
K. Ashida, M. Imaizumi, Y. Isaka, H. Moriwaki, K. Matushita, and O. Iichi
Complete Recanalization of Total Occlusion in Abdominal Aorta by Intra-aortic Infusion of a Thrombolytic Agent-- A Case Report
Angiology, July 1, 1993; 44(7): 574 - 579.
[Abstract] [PDF]

Home page
 ANGIOLOGYHome page
P. Poredos, D. Keber, and V. Videcnik
Late Results of Local Thrombolytic Treatment of Peripheral Arterial Occlusions
Angiology, November 1, 1989; 40(11): 941 - 947.
[Abstract] [PDF]

Home page
 ANGIOLOGYHome page
J. T. Mail, G. J. Becker, R. W. Holden, and H. Y. Yune
Interventional Radiology for Restoration of Vascular Patency in the Postoperative Patient Case Reports
Angiology, December 1, 1987; 38(12): 903 - 911.
[Abstract] [PDF]

Home page
 Am J Sports MedHome page
C. M. Vogel and J. E. Jensen
"Effort" thrombosis of the subclavian vein in a competitive swimmer
Am. J. Sports Med., July 1, 1985; 13(4): 269 - 272.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1983 by the Radiological Society of North America.