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Radiology, Vol 150, 701-702, Copyright © 1984 by Radiological Society of North America

ARTICLES

Transient focal liver scan defects in children receiving chemotherapy (pseudometastases). Work in progress

SJ Abramson, FS Barash, DW Seldin and WE Berdon

Three pediatric patients with tumors (two rhabdomyosarcoma, one Wilms tumor) had significant focal defects on Tc-99m sulfur colloid scans while receiving chemotherapy (all three had received chemotherapy, including actinomycin D, within ten days prior to scanning). In all three, the defects resolved spontaneously; one biopsy showed fibrosis of a mild degree. The finding of defects on liver scans of pediatric patients receiving chemotherapy must not be automatically assumed to be metastatic disease; the changes may relate to hepatic response to recently administered chemotherapy.




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