Radiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Coffey, R.
Right arrow Articles by Ballinger, W. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Coffey, R.
Right arrow Articles by Ballinger, W. B.

Radiology, Vol 151, 405-410, Copyright © 1984 by Radiological Society of North America

ARTICLES

The cerebrovascular effects of intraarterial CO2 in quantities required for diagnostic imaging

R Coffey, RG Quisling, JP Mickle, IF Hawkins Jr and WB Ballinger

The recent development of digital subtraction angiography (DSA) has renewed interest in the use of gases, especially carbon dioxide, as contrast agents. Both early physiologic studies and recent clinical reports suggest that arterial CO2-DSA is a safe and useful diagnostic tool in the examination of extremity circulation. The present study examined the neurologic sequelae, pathologic changes, and effects on the blood-brain barrier to intravenous Evans-Blue and horseradish peroxidase of intracarotid CO2, in albino rats. As with other forms of cerebral gas embolization, CO2 produced multifocal ischemic infarctions and disrupted the blood-brain barrier to macromolecular tracers. The site of the barrier lesion is the endothelial cell membrane, although the precise mechanisms of damage remain unknown. Caution must be urged in the use of CO2-DSA to avoid embolization of the central nervous system.


This article has been cited by other articles:


Home page
 J. Thorac. Cardiovasc. Surg.Home page
S. Martens, A. Theisen, J. O. Balzer, M. Dietrich, K. Graubitz, M. Scherer, C. Schmitz, M. Doss, and A. Moritz
Improved cerebral protection through replacement of residual intracavital air by carbon dioxide: A porcine model using diffusion-weighted magnetic resonance imaging
J. Thorac. Cardiovasc. Surg., January 1, 2004; 127(1): 51 - 56.
[Abstract] [Full Text] [PDF]

Home page
 ImagingHome page
D O Kessel, I Robertson, J V Patel, S Simpson, and E J Taylor
Angiographic strategies when iodinated contrast medium is undesirable
Imaging, December 15, 2001; 13(5): 349 - 356.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
L. Miskolczi, J. D. Flaherty, L. R. Guterman, and L. N. Hopkins
Carbon Dioxide Column Angioscopy: A New Endovascular Imaging Technique
AJNR Am. J. Neuroradiol., November 1, 2001; 22(10): 1849 - 1853.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
RADIOLOGY RADIOGRAPHICS RSNA JOURNALS ONLINE
Copyright © 1984 by the Radiological Society of North America.