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Radiology, Vol 151, 483-486, Copyright © 1984 by Radiological Society of North America

ARTICLES

Scintigraphic assessment of atrial function in patients with longstanding hypertension

A Marmor, A Frankel, DS Blondeheim, A Satinger and D Front

Right and left atrial function were assessed using Fourier analysis of gated radionuclide images in 14 normal subjects and 50 patients with long-standing essential hypertension. Slopes representing filling and early diastolic emptying were similar for both atria; however, early diastolic emptying of the left atrium was slowed markedly in the hypertensive group (42.6 +/- 18.6 counts/sec., vs. 79 +/- 16 in normal persons; p less than 0.001), implying a reduction in left ventricular compliance. The right ventricular ejection fraction was depressed in hypertensive patients compared with normal subjects (37.1 +/- 6% vs. 43.4 +/- 8.1%; p less than 0.01). These findings may be helpful in understanding the effect of hypertension on the left and right heart and could have prognostic and therapeutic implications as well.


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Left atrial Frank Starling law assessed by real-time, three-dimensional echocardiographic left atrial volume changes
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