Radiology, Vol 152, 161-166, Copyright © 1984 by Radiological Society of North America

ARTICLES

Peripheral arterial disease diagnosed with high-count-rate radionuclide arteriography

M Oshima, H Ijima, Y Kohda, K Kuramoto, Y Kikuchi, M Wada and M Akisada

Thirty-seven patients with peripheral vascular disease involving the legs were studied with first-pass peripheral radionuclide arteriography (RNA) and contrast arteriography to determine whether RNA could be used to evaluate perfusion of the toes. Data were acquired for 100 seconds using a multicrystal gamma camera following bolus injection of 30-35 mCi (1,110-1,295 MBq) of Tc-99m-labeled albumin during reactive hyperemia. Peripheral time-activity curves were examined and the time required for activity to decline to 75% of peak activity ( T75 ) was recorded. When an abnormal RNA was defined as T75 greater than or equal to 50 seconds, sensitivity was 92%, positive predictive accuracy 100%, and negative predictive accuracy 75%. These data suggest that peripheral RNA of the toes is a reliable, noninvasive procedure for evaluation of peripheral arterial disease; it can be valuable as a screening test prior to contrast arteriography as well as for follow-up.

This article has been cited by other articles:

				G. Baccelli, S. Terrani, P. Pacenti, E. Omboni, M. Bergonzi, P. Reggiani, F. Sardella, M. Catalano, and R. Bianchi Simultaneous Recording of Blood Volume Shifts in Different Vascular Beds in Man by a Versatile Scintigraphic Method Angiology, August 1, 1993; 44(8): 615 - 621. [Abstract] [PDF]

				D. Wilkinson, A. Parkin, P. Vowden, P. J. Robinson, and R. C. Kester Application of a New Method of Limb Blood Flow Measurement Using a Radioactive Isotope and a Gamma Camera Angiology, April 1, 1990; 41(4): 297 - 304. [PDF]