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Radiology, Vol 152, 435-442, Copyright © 1984 by Radiological Society of North America


ARTICLES

Mapping cerebral blood flow by xenon-enhanced computed tomography: clinical experience

H Yonas, WF Good, D Gur, SK Wolfson Jr, RE Latchaw, BC Good, R Leanza and SL Miller

Local cerebral blood flow was measured and mapped using xenon-enhanced x-ray transmission computed tomography. Studies involving 4-6 minutes of xenon-oxygen inhalation can be performed routinely in awake and anesthetized patients with acceptable patient tolerance and compliance. Several case studies of patients with acute and chronic ischemic injuries and other cerebral abnormalities are presented to illustrate characterization of flow pattern in normal and abnormal tissue, as well as the relevance of this flow information to clinical patient management.


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