Radiology, Vol 152, 527-529, Copyright © 1984 by Radiological Society of North America
Small-cell carcinoma of the lung: patterns of treatment failure in patients treated primarily by chemotherapy
MM Ali and TA Hazra
Treatment failure patterns in 75 patients with small-cell carcinoma of the
lung who were treated primarily by chemotherapy were reviewed. Of 10
patients with localized disease who underwent complete staging work- ups,
six had metastases to the chest, four to the central nervous system, four
to bone, and one to the lymph nodes. Of 32 patients with disease considered
to be localized but who did not undergo complete staging work-ups, 23 had
metastasis to the chest, 11 to the central nervous system, four to bone,
and two to the lymph nodes. Of 33 patients with documented distant
metastasis 23 had metastasis to the chest, 14 to the central nervous
system, 15 to bone, and six to the lymph nodes. Median survival times of
patients showing complete response to treatment was 17 months; for those
showing partial response it was 7 months.
