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Radiology, Vol 153, 349-352, Copyright © 1984 by Radiological Society of North America

ARTICLES

Bone lesions in systemic lupus erythematosus

RH Leskinen, BV Skrifvars, LS Laasonen and KJ Edgren

Routine joint radiographs of 125 patients with systemic lupus erythematosus were studied. A total of 121 patients had a clinical history of articular symptoms. Cystic bone lesions were found in 51 patients (41%). The lesions, which were typically located subchondrally in the small joints of hands and feet, appeared as well-defined radiolucent areas surrounded by either normal bone or a narrow sclerotic zone. Nutritional disturbance in the bones, caused by the vasculitis associated with systemic lupus erythematosus, is proposed as a possible pathogenetic mechanism of the cystic lesions.




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