Radiology, Vol 153, 375-377, Copyright © 1984 by Radiological Society of North America
Monooctanoin perfusion treatment of intrahepatic calculi
RJ Butch, RL MacCarty, PR Mueller, JT Ferrucci Jr, JF Simeone, SK Teplick and PH Haskin
Seventeen patients who had intrahepatic calculi underwent perfusion with
monooctanoin. While five patients responded with a decrease in size or
number of calculi, only one had a complete response; 12 showed no response;
and one died during the perfusion (however, the perfusion was not believed
to have contributed to the death). Fifteen of the 17 patients required
further treatment by a combination of basket extraction, oral
administration of chenodeoxycholic acid, or surgery. The lack of response
to monooctanoin perfusion was in part due to calculus composition. Because
of the poor response to this treatment and the prolonged hospitalization
generally required, monooctanoin is not recommended for dissolution of
intrahepatic calculi.
