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Radiology, Vol 155, 655-657, Copyright © 1985 by Radiological Society of North America

ARTICLES

Supraclinoid intracarotid chemotherapy using a flow-directed soft- tipped catheter

C Charnsangavej, Y Lee, CH Carrasco, LG Feun, RA Tang, K Wright, S Wallace and C Gianturco

In an attempt to avoid toxic reactions of the eye as a complication of internal carotid arterial infusion of cisplatin, carmustine, or a combination of both for the treatment of brain tumors, a new Gore- Tex/Teflon coaxial catheter system has been used for supraclinoid placement. Catheter placement was successful in 14 of 16 attempts in eight patients. Two patients experienced eye pain and conjunctivitis--a result of the chemotherapeutic agent leaking through the Gore-Tex portion of the catheter at the infusion rate of 170 ml/h. No complications were noted as long as the infusion rate was maintained at 125 ml/h or lower.




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